This article looks at some realities and lessons from Oxfam as a confederation of non-government organisations, working together on gender inequality. It looks at how the individual affiliates have gone about strengthening our collective contribution to transformation of gender and power relations in the different environments we work in, and reflects on learning that can be taken away. It draws on the author's experience as Gender Justice Lead for Oxfam International, which provides leadership, co-ordination and support to the confederation's programmes, campaign, monitoring, evaluation, and learning. It concludes that there are powerful possibilities along with important challenges in working as a confederation to make the concerns and interests of women central to development practice.